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Pills and potions chords10/31/2023 ![]() ![]() Meikle and colleagues (this issue) enter this spiky debate, looking at psilocybin. Ketamine is now (almost) mainstream, cannabis legalised and marketed in many jurisdictions, stimulants are again in the Lazarus zone, and psychedelics are the latest carriage on this lengthening train. For this reason, there is growing interest, maybe even fervour, in repurposing drugs hitherto regarded as agents of abuse. ![]() An overview of industry-initiated trials shows a dramatic slowdown of novel therapy development over the last decade, especially the last 5 years. There is a crisis in novel therapy development.
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